GENERAL CATALOGUE
Thiocolchicine
HY-116852 · 5 mg
MedChemExpress · Cat: HY-116852
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medchemexpress.com/thiocolchicine.htmlCatalog No: HY-116852
CAS No: 2730-71-4
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Thiocolchicine, a derivative modified in the C Ring of Colchicine HY-16569 with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization IC50=2.5 AAasAasAAmuM and competitively binds to tubulin with a Ki of 0.7 AAasAasAAmuM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
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