GENERAL CATALOGUE
THR-? agonist 9
HY-174887 · 50 mg
MedChemExpress · Cat: HY-174887
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Manufacturer product page
medchemexpress.com/thr-%CE%B2-agonist-9.htmlCatalog No: HY-174887
CAS No: 2920045-74-3
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
THR-? agonist 9 is a potent, selective, and His435 mutation-sensitive THR-? EC50: 3.2 nM agonist. THR-? agonist 9 has moderate selectivity approximately 10-fold and good activation capacity EC50: 134.2 nM to 515.5 nM for multiple His435 mutants H435A, H435Y, and H435R . THR-? agonist 9 has the potential to be used in the study of dyslipidemia, metabolic dysfunction-associated steatohepatitis MASH , or resistance to thyroid hormone RTH .
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