Thrombomodulin Rabbit Monoclonal Antibody

Description

EnkiLife offers the Thrombomodulin Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF,IP application. Alternative Names of Immunogen: CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice. Research Area: Cardiovascular