GENERAL CATALOGUE
THX6
HY-172199 · 5 mg
MedChemExpress · Cat: HY-172199
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medchemexpress.com/thx6.htmlCatalog No: HY-172199
CAS No: 3076954-42-9
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
THX6 is the activator for human mitochondrial protease ClpP with an EC50 of 1.18 ?M. THX6 exhibits cytotoxicity in ONC201-resistant cell SU-DIPG-VI with IC50 of 0.13 ?M. THX6 inhibits the expression of mitochondrial-related proteins such as parkin, TFAM, NRF1, SDHA , leads to impaired mitochondrial function. THX6 affects the lipid metabolism in cell membran, and exhibits antitumor potential.