Thyroglobulin (18M5) Rabbit Monoclonal Antibody

Description

EnkiLife offers the Thyroglobulin (18M5) Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,ICC/IF,FC application. Alternative Names of Immunogen: AITD3; hTG; TDH3; Tg; TGN; Thyroglobulin;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2000-1:10000,IHC 1:200-1:500,ICC/IF 1:20-1:50,FC 1:50-1:100 Background: Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030). One dimer produces 7 thyroid hormone molecules (PubMed:32025030).