Thyroglobulin (4G11) Rabbit Monoclonal Antibody

Description

EnkiLife offers the Thyroglobulin (4G11) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC application. Alternative Names of Immunogen: AITD3; hTG; TDH3; Tg; TGN; Thyroglobulin;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2000-1:20000,IHC 1:200-1:500 Background: Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030). One dimer produces 7 thyroid hormone molecules (PubMed:32025030).