

HY-114570 · 1 mg
MedChemExpress · Cat: HY-114570
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medchemexpress.com/tiazofurin.htmlDescription
Tiazofurin NSC 286193 is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide TAD , a potent inhibitor of IMP dehydrogenase IMPDH . Tiazofurin enhances the autosecretion of IL-6 in K562 cells. Tiazofurin also has anti-orthopoxvirus and anti-variola activities. Tiazofurin can be used for the study of leukemia and lung cancer.







