GENERAL CATALOGUE
Ticlopidine
HY-100386 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100386
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Catalog No: HY-100386
CAS No: 55142-85-3
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ticlopidine PCR 5332 , an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 ?M. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 ?M and 149 ?M for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 ?M, respectively.
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