GENERAL CATALOGUE
Tigilanol tiglate
HY-109076 · 250 g
MedChemExpress · Cat: HY-109076
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medchemexpress.com/tigilanol-tiglate.htmlCatalog No: HY-109076
CAS No: 943001-56-7
Category: Apoptosis
Pack Size: 250 g
Brand: MedChemExpress
Description
Tigilanol tiglate EBC-46 is a protein kinase C PKC /C1 domain activator. Tigilanol tiglate is associated with mitochondrial/endoplasmic reticulum ER dysfunction, leading to activation of the unfolded protein response UPRmt/ER and subsequent induction of ATP depletion, organelles expansion, Caspase activation, gasdermin E cleavage, and terminal necrosis. Tigilanol tiglate, as a small anti-tumor molecule with immunomodulatory effects, can be used in the study of head and neck squamous cell carcinoma and soft tissue sarcoma.
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