GENERAL CATALOGUE
TIM-3-IN-2
HY-155175 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155175
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medchemexpress.com/tim-3-in-2.htmlCatalog No: HY-155175
CAS No: 1113126-49-0
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
TIM-3-IN-2 Compound A-41 is a Tim3 inhibitor KD: 0.61 ?M . TIM-3-IN-2 blocks TIM-3 interactions with PtdSer, CEACAM1, and Gal-9. TIM-3-IN-2 inhibits the immunosuppressive function of TIM-3. TIM-3-IN-2 reverses the TIM-3-mediated blockade of the production of proinflammatory cytokines, and maximizes the T-cell antitumor activity against AML cell lines.
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