GENERAL CATALOGUE
Timapiprant
HY-15342 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15342
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medchemexpress.com/oc000459.html
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Catalog No: HY-15342
CAS No: 851723-84-7
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Timapiprant OC000459 is a potent, selective, and orally active D prostanoid receptor 2 DP2, also known as CRTH2 antagonist. Timapiprant OC000459 potently displaces 3H PGD2 from human recombinant DP2 Ki=13 nM , rat recombinant DP2 Ki=3 nM , and human native DP2 Ki=4 nM . Timapiprant OC000459 inhibits mast cell activation of Th2 lymphocytes and eosinophils.
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