

HY-15342A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15342A
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medchemexpress.com/timapiprant-sodium.htmlDescription
Timapiprant sodium OC000459 sodium is a potent, selective, and orally active D prostanoid receptor 2 DP2, also known as CRTH2 antagonist. Timapiprant sodium OC000459 sodium potently displaces 3H PGD2 from human recombinant DP2 Ki=13 nM , rat recombinant DP2 Ki=3 nM , and human native DP2 Ki=4 nM . Timapiprant sodium OC000459 sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils.