Tip5 Rabbit Polyclonal Antibody

Description

EnkiLife offers the Tip5 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,IHC application. Alternative Names of Immunogen: BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:50-1:300 Background: function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. sequence caution:Contaminating sequence. Potential poly-A sequence. similarity:Belongs to the WAL family. similarity:Contains 1 bromo domain. similarity:Contains 1 DDT domain. similarity:Contains 1 MBD (methyl-CpG-binding) domain. similarity:Contains 1 PHD-type zinc finger. similarity:Contains 4 A.T hook DNA-binding domains. subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex). tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.