GENERAL CATALOGUE
TL12-186
HY-130665 · 5 mg
MedChemExpress · Cat: HY-130665
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Catalog No: HY-130665
CAS No: 2250025-88-6
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
TL12-186 is a Cereblon-dependent multi-kinase PROTAC degrader. Multi-kinases include CDK, BTK, FLT3, Aurora kinases, TEC, ULK, ITK, et al. TL12-186 inhibits CDK2/cyclin A IC50=73 nM and CDK9/cyclin T1 IC50=55 nM .
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