TLE4 Rabbit Polyclonal Antibody

Description

EnkiLife offers the TLE4 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: TLE4; KIAA1261; Transducin-like enhancer protein 4. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 Background: caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation. function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. similarity:Belongs to the WD repeat Groucho/TLE family. similarity:Contains 7 WD repeats. subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2. tissue specificity:In all tissues examined, mostly in brain, and muscle.