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TLR7/8/9 antagonist 2
GENERAL CATALOGUE

TLR7/8/9 antagonist 2

HY-153460 · 50 mg

MedChemExpress · Cat: HY-153460

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Catalog No: HY-153460
CAS No: 2920729-91-3
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

TLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist. TLR7/8/9 antagonist 2 has inhibitory activities for HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC50 values of 0.011 ?M, 0.029 ?M and 0,052 ?M, respectively.TLR7/8/9 antagonist 2 has high bioavailability in vivo.TLR7/8/9 antagonist 2 can be used for the research of auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.

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