GENERAL CATALOGUE
TLR7/8 antagonist 2
HY-144619 · 5 mg
MedChemExpress · Cat: HY-144619
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Catalog No: HY-144619
CAS No: 2769085-03-0
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
TLR7/8 antagonist 2 Compound 15 is a potent and orally active agonist of TLR7/8 with IC50s of 4.9 and 0.6 nM, respectively. Inappropriate activation of TLR7 and TLR8 is linked to several autoimmune diseases, such as lupus erythematosus. TLR7/8 antagonist 2 has the potential for the research of autoimmune diseases.
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