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TLR7 agonist 21
GENERAL CATALOGUE

TLR7 agonist 21

HY-163670 · 50 mg

MedChemExpress · Cat: HY-163670

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Catalog No: HY-163670
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

TLR7 agonist 21 Compound 27B is a selective agonist for Toll-like receptor 7 TLR7 , with an EC50 of 17.53 nM for human TLR7 and 41.7 nM for mouse TLR7 . TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6, TNF-?, IFN-?1, and IL-4. TLR7 agonist 21 acts as a vaccine adjuvant, increases levels of IgG and IgA, and protects the mouse from influenza virus infections.

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