GENERAL CATALOGUE
TLR7 agonist 22
HY-162579 · 50 mg
MedChemExpress · Cat: HY-162579
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Catalog No: HY-162579
CAS No: 3036114-68-5
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
TLR7 agonist 22 Compound 11a emerges as a selective TLR7 agonist with an IC50 value of 25.86 ?M. TLR7 agonist 22 inhibits the cellular HBsAg secretion and effectively activates TLR7, thereby inducing the secretion of TLR7-regulated cytokines IL-12, TNF-?and IFN-?in human PBMC cells. TLR7 agonist 22 is a promising for research in the field of developing novel immunomodulatory anti-HBV agents.
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