GENERAL CATALOGUE
TLR7 agonist 29
HY-173070 · 50 mg
MedChemExpress · Cat: HY-173070
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medchemexpress.com/tlr7-agonist-29.htmlCatalog No: HY-173070
CAS No: 2275612-76-3
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress
Description
TLR7 agonist 29 Compound 1 is the agonist for TLR7 with an EC50 of 5.2 nM for human TLR7 EC50 for mouse TLR7 is 48.2 nM . TLR7 agonist 29 activates bone marrow-derived macrophages BMDMs , stimulates myeloid cells in the tumor microenvironment, promotes the expression of PD-L1, CD86 and IFN-?. TLR7 agonist 29 can be used as payload for synthesis of ADC.
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