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TLR8 agonist 7
GENERAL CATALOGUE

TLR8 agonist 7

HY-161629 · 50 mg

MedChemExpress · Cat: HY-161629

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Catalog No: HY-161629
CAS No: 3034750-26-7
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

TLR8 agonist 7 Compound II-36 is an agonist for Toll-like receptor 8 TLR8 with EC50 250 nM. TLR8 agonist 7 is stable in human and murine plasma, induces secretion of cytokines TNF?, with EC50 <1 ?M. TLR8 agonist 7 exhibits antitumor activity in MC38-HER2 xenograft mouse model with a tumor growth inhibition TGI rate of 98 %.

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