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TLR8 agonist 9
GENERAL CATALOGUE

TLR8 agonist 9

HY-161631 · 50 mg

MedChemExpress · Cat: HY-161631

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Catalog No: HY-161631
CAS No: 3034750-61-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

TLR8 agonist 9 Compound II-77 is an agonist for Toll-like receptor 8 TLR8 with EC50 of 0.25-1 ?M. TLR8 agonist 9 is stable in human and murine plasma, induces secretion of cytokines TNF?, with EC50 1 ?M. TLR8 agonist 9 exhibits antitumor activity in MC38-HER2 xenograft mouse model with a tumor growth inhibition TGI rate of 97 %.

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