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TM471-1
GENERAL CATALOGUE

TM471-1

HY-174129 · 50 mg

MedChemExpress · Cat: HY-174129

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medchemexpress.com/tm471-1.html
Catalog No: HY-174129
CAS No: 2649008-95-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

TM471-1 is an orally active and covalent Brutons tyrosine kinase BTK inhibitor with IC50 values of 1.3 nM BTKWT , >40,000 nM BTKC481S , 7.9 nM TEC and 12.4 nM TXK . TM471-1 inhibits cell growth in vivo and in vitro, arrests cell cycle at G0/G1 phase and induces cell apoptosis.

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