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TNF-?-IN-11
GENERAL CATALOGUE

TNF-?-IN-11

HY-149331 · 50 mg

MedChemExpress · Cat: HY-149331

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Catalog No: HY-149331
CAS No: 2945197-77-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

TNF-?-IN-11 Compound 10 is a TNF-? inhibitor with a KD value of 12.06 ?M. TNF-?-IN-11 binds to TNF-? and blocks the activation of TNF-?-trigged caspase and NF-?B signaling pathway. TNF-?-IN-11 inhibits the phosphorylation of I?B?, as well as the nuclear translocation of NF ?B p65. TNF-?-IN-11 can be used for research of TNF-?-mediated autoimmune diseases.

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