

HY-149331 · 50 mg
MedChemExpress · Cat: HY-149331
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medchemexpress.com/tnf-%CE%B1-in-11.htmlDescription
TNF-?-IN-11 Compound 10 is a TNF-? inhibitor with a KD value of 12.06 ?M. TNF-?-IN-11 binds to TNF-? and blocks the activation of TNF-?-trigged caspase and NF-?B signaling pathway. TNF-?-IN-11 inhibits the phosphorylation of I?B?, as well as the nuclear translocation of NF ?B p65. TNF-?-IN-11 can be used for research of TNF-?-mediated autoimmune diseases.







