

HY-114573 · 1 mg
MedChemExpress · Cat: HY-114573
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medchemexpress.com/tnf-%CE%B1-in-19.htmlDescription
TNF-?-IN-19 is an inhibitor of TNF? that can block the interaction between TNF?RI, TRADD, and RIP1, the EC50 values for TNF?, IL-1?, and IL-1?/TNF? are 2.451, 3.792 and 1.54 ?M, respectively. TNF-?-IN-19 only inhibits the degradation of I?B? when cells are stimulated by TNF? and not by IL-1?.