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TNF-?-IN-2
GENERAL CATALOGUE

TNF-?-IN-2

HY-134471 · 5 mg

MedChemExpress · Cat: HY-134471

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Catalog No: HY-134471
CAS No: 2074702-04-6
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

TNF-?-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha TNF? , with an IC50 of 25 nM in the HTRF assay. TNF-?-IN-2 distorts the TNF? trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-?-IN-2 can be used for the research of rheumatoid arthritis.

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