TNFRSF11B Mouse Monoclonal Antibody

Description

EnkiLife offers the TNFRSF11B Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA application. Alternative Names of Immunogen: OPG; TR1; OCIF; MGC29565; TNFRSF11B. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000 Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Research Area: Apoptosis