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TNI-97
GENERAL CATALOGUE

TNI-97

HY-175030 · 50 mg

MedChemExpress · Cat: HY-175030

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medchemexpress.com/tni-97.html
Catalog No: HY-175030
CAS No: 2790425-52-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

TNI-97 is a selective and orally active HDAC6 inhibitor, with an IC50 of 0.2 nM. TNI-97 potently inhibited TNBC cell MDA-MB-453 growth and clonogenicity. TNI-97 induces PANoptosis including apoptosis, necroptosis and pyroptosis in MDA-MB-453 cells. TNI-97 shows antitumor activity in the mice carrying the MDA-MB-453 xenograft or carrying murine-derived TNBC cell allografts. TNI-97 can be used for the study of triple-negative breast cancer.

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