GENERAL CATALOGUE
Top/HDAC-IN-1
HY-145851 · 50 mg
MedChemExpress · Cat: HY-145851
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Manufacturer product page
medchemexpress.com/top-hdac-in-1.htmlCatalog No: HY-145851
CAS No: 2775446-49-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Top/HDAC-IN-1 Compound 29b is a topoisomerase/HDAC dual inhibitor with IC50s of 18, 230, 790, 87, and 5250 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. Top/HDAC-IN-1 exhibits potent antitumor activities against the HCT116 cell line with the IC50 of 180 nM. Top/HDAC-IN-1 efficiently induces apoptosis with G2 cell cycle arrest in HCT116 cells.
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