

HY-161957 · 50 mg
MedChemExpress · Cat: HY-161957
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medchemexpress.com/top1-2-in-1.htmlDescription
Top1/2-IN-1 compound 23 is an orally available dual inhibitor of Top1/2 with antiproliferative activity. Top1/2-IN-1 damages DNA with increased levels of reactive oxygen species, inducing apoptosis and cell cycle arrest in cancer cells. Top1/2-IN-1 exhibits in vivo antitumor activity in xenograft models.





