GENERAL CATALOGUE
Topobexin
HY-174374 · 5 mg
MedChemExpress · Cat: HY-174374
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Catalog No: HY-174374
CAS No: 3076446-44-8
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
Topobexin Topobexin 9 is a highly selective inhibitor for TOP2B. Topobexin selectively inhibits TOP2B in vitro and immobilizes TOP2B on DNA. Topobexin demonstrates significant protection of cardiomyocytes against DAU-induced damage. Topobexin prevents anthracycline-induced cardiotoxicity and DAU-induced decrease in LV systolic function in vivo with rabbit model.
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