BioMall
Brand Store/MedChemExpress/TOPOI/PARP-1-IN-2
TOPOI/PARP-1-IN-2
GENERAL CATALOGUE

TOPOI/PARP-1-IN-2

HY-169299 · 50 mg

MedChemExpress · Cat: HY-169299

Reach 3+ verified distributors

Catalog No: HY-169299
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

TOPOI/PARP-1-IN-2 compound 6c is a dual PARP-1 and topoisomerase 1 TOPO-1 inhibitor with IC50s of 32.2 nM and 46.2?nM, respectively. TOPOI/PARP-1-IN-2 shows a selectivity for PARP-1 over PARP-2. TOPOI/PARP-1-IN-2 disrupts the cell cycle at the S phase and induces apoptosis in NCI-60 cancer cell lines.

More from MedChemExpress

2-Bromohexadecanoic acid
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HDAC-IN-84
HY-170379
Apoptosis