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Torin 1, mTOR inhibitor
ab218606 · 5 mg
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Catalog No: ab218606
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 607.6 Da, Purity >98 %. Potent, selective, ATP-competitive mTOR inhibitor that directly inhibits both mTORC1 and mTORC2 complexes, with IC50 values between 2 and 10 nM in in vitro kinase assays. Displays 1000-fold selectivity for mTOR over PI3K, 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34, and exhibits 100-fold binding selectivity relative to 450 other protein kinases. Impairs cell growth and proliferation.
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