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Totrombopag
GENERAL CATALOGUE

Totrombopag

HY-14756 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-14756

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Manufacturer product page

medchemexpress.com/totrombopag.html
Catalog No: HY-14756
CAS No: 376592-42-6
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Totrombopag is an orally effective thrombopoietin receptor TpoR agonist. By activating TpoR, Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology.

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