GENERAL CATALOGUE
Toyocamycin
HY-103248 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103248
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Catalog No: HY-103248
CAS No: 606-58-6
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Toyocamycin Vengicide is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1?-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1? auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM.
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