GENERAL CATALOGUE
TRAP1-IN-1
HY-155063 · 5 mg
MedChemExpress · Cat: HY-155063
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Catalog No: HY-155063
CAS No: 3031102-94-7
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
TRAP1-IN-1 compound 35 is a potent and selective inhibitor of TRAP1?a mitochondrial isoform of Hsp90. TRAP1-IN-1 has >250-fold TRAP1 selectivity over Grp94?and disrupts TRAP1 tetramer stability?induces TRAP1 client protein degradation. TRAP1-IN-1 also inhibits mitochondrial complex I of oxidative phosphorylation OXPHOS?disrupts the mitochondrial membrane potential?and enhances glycolysis metabolism.
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