GENERAL CATALOGUE
TREM2-IN-1
HY-160421 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-160421
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Manufacturer product page
medchemexpress.com/trem2-in-1.htmlCatalog No: HY-160421
CAS No: 2000236-36-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
TREM2-IN-1 OPA is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206+ and CX3CR1+ immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells.