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Tri-GalNAc-DBCO
GENERAL CATALOGUE

Tri-GalNAc-DBCO

HY-148476 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-148476

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Catalog No: HY-148476
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Tri-GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Tri-GalNAc-DBCO can undergo strain-promoted alkyne-azide cycloaddition SPAAC reactions with molecules containing an azide group. Tri-GalNAc-DBCO specifically binds to the asialoglycoprotein receptor ASGPR . Tri-GalNAc-DBCO directs the conjugated molecule to the lysosome for degradation via receptor-mediated endocytosis. Tri-GalNAc-DBCO can be used in the study of liver-related diseases.

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