GENERAL CATALOGUE
Triclosan
HY-B1119 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-B1119
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medchemexpress.com/Triclosan.htmlCatalog No: HY-B1119
CAS No: 3380-34-5
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase FabI step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase FabI and FabI containing a glycine-to-valine substitution at position 93 FabIG93V with IC50s of 2 AAasAasAAmuM and 10 AAasAasAAmuM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells NSC . Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models.
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