Triclosan (Standard)

Description

Triclosan Standard is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase FabI step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase FabI and FabI containing a glycine-to-valine substitution at position 93 FabIG93V with IC50s of 2 AAasAasAAmuM and 10 AAasAasAAmuM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells NSC . Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models.