TRIM25 Mouse Monoclonal Antibody

Description

EnkiLife offers the TRIM25 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: EFP; Z147; RNF147; ZNF147. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:250,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.