Trimetazidine-d9 dihydrochloride

Description

Trimetazidine-d9 dihydrochloride is deuterium labeled Trimetazidine dihydrochloride . Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit ?-oxidation of free fatty acid FFA . Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase HADHA inhibitor.