GENERAL CATALOGUE
Trimetazidine
HY-B0968A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0968A
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Catalog No: HY-B0968A
CAS No: 5011-34-7
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit ?-oxidation of free fatty acid FFA . Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase HADHA inhibitor.
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