GENERAL CATALOGUE
Trimethylamine N-oxide dihydrate
HY-108915 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-108915
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medchemexpress.com/trimethylamine-oxide-dihydrate.htmlCatalog No: HY-108915
CAS No: 62637-93-8
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-?/smad2 signaling pathway.
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