

HY-10373 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10373
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Manufacturer product page
medchemexpress.com/Trimetrexate.html
Description
Trimetrexate CI-898 is an antibiotic, also a potent and orally active dihydrofolate reductase DHFR inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia PCP and cancer.







