GENERAL CATALOGUE
Trovafloxacin mesylate
HY-103399 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103399
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medchemexpress.com/trovafloxacin-mesylate.htmlCatalog No: HY-103399
CAS No: 147059-75-4
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel PANX1 inhibitor with an IC50 of 4 ?M for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1.
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