GENERAL CATALOGUE
TrxR-IN-3
HY-146307 · 50 mg
MedChemExpress · Cat: HY-146307
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medchemexpress.com/trxr-in-3.htmlCatalog No: HY-146307
CAS No: 2445565-58-0
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
TrxR-IN-3 Compound 2c is a potent inhibitor of TrxR. TrxR-IN-3 exhibits potent antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and resulted in marked apoptosis by regulating apoptosis-related proteins expressed in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and diminishing the expression of LC3-I and p62 proteins.
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