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TrxR-IN-8
GENERAL CATALOGUE

TrxR-IN-8

HY-173403 · 50 mg

MedChemExpress · Cat: HY-173403

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medchemexpress.com/trxr-in-8.html
Catalog No: HY-173403
CAS No: 2857180-28-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

TrxR-IN-8 Compound 6f is a selective TrxR inhibitor IC50: 10.2 ?M . TrxR-IN-8 induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species ROS , reducing intracellular thiols, and lowering the glutathione/glutathione ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer NSCLC cells.

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