GENERAL CATALOGUE
TT-012
HY-156483 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-156483
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medchemexpress.com/tt-012.html
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Catalog No: HY-156483
CAS No: 1164471-33-3
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
TT-012 specifically binds to dynamic MITF and destroys the latters dimer formation and DNA-binding ability. TT-012 inhibits the transcriptional activity of MITF in B16F10 melanoma cells. TT-012 inhibits the growth of high-MITF melanoma cells, and inhibits the tumor growth and metastasis with tolerable toxicity to liver and immune cells in animal models.
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