Tubastatin A

Description

Tubastatin A GMP is the Tubastatin A HY-13271A produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective 1000-fold more against all other isozymes except HDAC8 57-fold more . Tubastatin A also inhibits HDAC10 and metallo-?-lactamase domain-containing protein 2 MBLAC2 .